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Rbm8a deficiency causes hematopoietic defects by modulating Wnt/PCP signaling.
Kocere A, Chiavacci E, Soneson C, Wells HH, Méndez-Acevedo KM, MacGowan JS, Jacobson ST, Hiltabidle MS, Raghunath A, Shavit JA, Panáková D, Williams MLK, Robinson MD, Mosimann C, Burger A. Kocere A, et al. Among authors: wells hh. bioRxiv [Preprint]. 2024 Feb 1:2023.04.12.536513. doi: 10.1101/2023.04.12.536513. bioRxiv. 2024. PMID: 37090609 Free PMC article. Preprint.
PU.1 is required to restrain myelopoiesis during chronic inflammatory stress.
Chavez JS, Rabe JL, Niño KE, Wells HH, Gessner RL, Mills TS, Hernandez G, Pietras EM. Chavez JS, et al. Among authors: wells hh. Front Cell Dev Biol. 2023 Jun 26;11:1204160. doi: 10.3389/fcell.2023.1204160. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37497478 Free PMC article.
The genetic background significantly impacts the severity of kidney cystic disease in the Pkd1RC/RC mouse model of autosomal dominant polycystic kidney disease.
Arroyo J, Escobar-Zarate D, Wells HH, Constans MM, Thao K, Smith JM, Sieben CJ, Martell MR, Kline TL, Irazabal MV, Torres VE, Hopp K, Harris PC. Arroyo J, et al. Among authors: wells hh. Kidney Int. 2021 Jun;99(6):1392-1407. doi: 10.1016/j.kint.2021.01.028. Epub 2021 Mar 9. Kidney Int. 2021. PMID: 33705824 Free PMC article.